multi-well microelectrode array (mwmea) plates Search Results


microelectrode array (mwmea) plates  (Axion BioSystems)
90
Axion BioSystems microelectrode array (mwmea) plates
Microelectrode Array (Mwmea) Plates, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mea plate  (Axion BioSystems)
90
Axion BioSystems mea plate
Mea Plate, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
mea plate - by Bioz Stars, 2026-10
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multi-well microelectrode array (mwmea) plates  (Axion BioSystems)
90
Axion BioSystems multi-well microelectrode array (mwmea) plates
Multi Well Microelectrode Array (Mwmea) Plates, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
multi-well microelectrode array (mwmea) plates - by Bioz Stars, 2026-10
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multi-well microelectrode (mwmea) plates  (Axion BioSystems)
90
Axion BioSystems multi-well microelectrode (mwmea) plates
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Multi Well Microelectrode (Mwmea) Plates, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multi-well+microelectrode+array+(mwmea)+plates/multi+well+microelectrode++mwmea++plates/pmc06438628-117-3-12
Average 90 stars, based on 1 article reviews
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multi-well microelectrode plates  (Axion BioSystems)
90
Axion BioSystems multi-well microelectrode plates
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Multi Well Microelectrode Plates, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multi-well+microelectrode+array+(mwmea)+plates/multi+well+microelectrode+plates/pmc07371233-89-8-17
Average 90 stars, based on 1 article reviews
multi-well microelectrode plates - by Bioz Stars, 2026-10
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multi-(48) well mea mwmea  (Axion BioSystems)
90
Axion BioSystems multi-(48) well mea mwmea
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Multi (48) Well Mea Mwmea, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1,2,4-triazole  (Enamine Ltd)
90
Enamine Ltd 1,2,4-triazole
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
1,2,4 Triazole, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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estradiol  (Enamine Ltd)
99
Enamine Ltd estradiol
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Estradiol, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pha-543613  (Enamine Ltd)
90
Enamine Ltd pha-543613
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Pha 543613, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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genistein  (Enamine Ltd)
99
Enamine Ltd genistein
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Genistein, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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wistar han rat  (Inotiv)
96
Inotiv wistar han rat
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Wistar Han Rat, supplied by Inotiv, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fluconazole  (Enamine Ltd)
99
Enamine Ltd fluconazole
A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in <t>primary</t> <t>cortical</t> <t>cultures</t> grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.
Fluconazole, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in primary cortical cultures grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.

Journal: Archives of toxicology

Article Title: Screening the ToxCast Phase II Libraries for Alterations in Network Function using Cortical Neurons Grown on Multi-well Microelectrode Array (mwMEA) Plates

doi: 10.1007/s00204-017-2035-5

Figure Lengend Snippet: A total of 1055 unique compounds from EPA’s ToxCast Phase 2 libraries were screened at a single concentration (40 μM) in primary cortical cultures grown on mwMEA plates to determine acute (40 min) effects on neural network function. Top: A total of 325 compounds altered network firing rates (MFR) beyond threshold with 308 compounds decreasing activity. In addition to decreasing activity, 8 of these compounds were also cytotoxic. A total of 18 compounds (including bicuculline methiodide) increased MFR, while 730 compounds did not alter MFR beyond either threshold. Middle: Of the 326 compound identified as hits in the mwMEA assay, 253 compounds (~78%) were categorized for use in five major categories within ToxCast. These categories were pesticides (52), pharmaceuticals (86), fungicides (48), herbicides (35), and chemical intermediates (32). Bottom: A total of 121 compounds (including bicuculline methiodide) out of the 326 total hits could be assigned to gene targets or modes of action (Supplemental Table 4). Shown here are any target genes/MOAs that contained 5 or more compounds, and the total number of compounds assigned to that category. Of the 205 compounds not represented, 87 did not have an assigned target gene/MOA in CPCat.

Article Snippet: Prior to plating rat primary cortical cultures, multi-well microelectrode (mwMEA) plates from Axion Biosystems Inc. (Atlanta, GA) were prepared for culture by coating with polyethyleneamine as previously described ( Valdivia et al., 2014 ).

Techniques: Concentration Assay, Activity Assay, Pesticides